Description
This triple-active topical solution combines dutasteride 0.025%, minoxidil 5%, and tretinoin 0.01% for localized scalp application. Dutasteride provides dual type I and type II 5-alpha-reductase inhibition, minoxidil supports follicular activity through vasodilation, and tretinoin promotes scalp cell turnover and follicular responsiveness. Thanks to its Trichosol base, the solution is devoid of ethanol and propylene glycol, and is thus skin friendly.
Standard twice-daily use at 1mL per application results in a total daily exposure of 0.5mg of dutasteride, approaching the threshold between localized scalp activity and broader systemic influence. Total daily tretinoin exposure is 0.2mg. A 50mL bottle corresponds to approximately 25 days of standard use.
Composition (50mL): Trichosol q.s. ad 50mL; Ethoxy Diglycol (Transcutol P) 5mL; Distilled Water 5mL; Minoxidil 2.5g (50mg/mL); Dutasteride 12.5mg (0.25mg/mL); Tretinoin 5mg (0.1mg/mL); Sodium Benzoate 50mg; Butylated Hydroxytoluene (BHT) 50mg.
